|Can't stop playing with the interface!|
A more vertical control layout made it much more practical. Except I never liked the Action Bar location. It was aesthetically unpleasing, sticking out at the bottom of my nice clean layout. Even worse, at the extreme bottom right of the screen, it's hard to keep an eye on the ability recharge while fighting.
Tried a number of rearrangements, but wasn't happy with most of them. Finally got a good one last night. It MIGHT replace the previous favorite.
I gave up a smidgen of width on the 3-d game screen. Made the Ability Bar vertical, shortened the minimap a little. The inventory/equip/prayer/misc window is taller, but narrower. It actually has more room. The Tools menu is now vertical, and on the bottom right of the screen. Hopefully it's out of the way of accidental clicks. Lengthened the Chat window to give a nice even vertical line all the way down. With the added advantage of having a better width on the chat window.
It seems a good compromise. I've lost a tiny amount of 3-d screen space, but kept everything easy-to-access. Can keep an eye on combat abilities as they recharge. And it has a nice clean vertical area for all the control windows to fit into.
It would be nice if I had just a bit more screen real estate. On the other hand, my current screen resolution works well on the computer. Maybe this layout will last for a while.